N,1-二甲基色胺

N,1-二甲基色胺
英文名	N,1-Dimethyltryptamine
别名	N,N'-二甲基色胺
识别
CAS号	37637-29-9
性质
化学式	C12H16N2
摩尔质量	188.27 g·mol−1
溶解性（水）	可溶于水（1.8 g，25 °C），易溶于酸
	若非注明，所有数据均出自一般条件（25 ℃，100 kPa）下。

N,1-二甲基色胺是一种有机化合物，化学式为C₁₂H₁₆N₂，它是二甲基色胺的同分异构体之一，为芳环氮和氨基氮上的氢各被一个甲基取代的产物。它可由N-叔丁氧羰基-N,1-二甲基色胺在三氟乙酸的二氯甲烷溶液中脱Boc保护得到^[2]，或由相应的酰胺还原得到。^[3]它的氨基氮上可以进一步甲基化，得到季铵盐。^[2]

参考文献

↑ Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2021 ACD/Labs). Retrieved from SciFinder. [2021-07-22].
↑ ^2.0 ^2.1 Edwin G. Pérez, Bruce K. Cassels, Christoph Eibl, Daniela Gündisch. Synthesis and evaluation of N1-alkylindole-3-ylalkylammonium compounds as nicotinic acetylcholine receptor ligands. Bioorganic & Medicinal Chemistry. 2012-06, 20 (12): 3719–3727 [2021-07-22]. doi:10.1016/j.bmc.2012.04.050 （英语）.
↑ Christopher R. Jamison, Joseph J. Badillo, Jeffrey M. Lipshultz, Robert J. Comito, David W. C. MacMillan. Catalyst-controlled oligomerization for the collective synthesis of polypyrroloindoline natural products. Nature Chemistry. 2017-07-24, 9 (12): 1165–1169 [2021-07-22]. ISSN 1755-4330. doi:10.1038/nchem.2825.

[1] Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2021 ACD/Labs). Retrieved from SciFinder. [2021-07-22].

[Perez-2] 2.0 ^2.1 Edwin G. Pérez, Bruce K. Cassels, Christoph Eibl, Daniela Gündisch. Synthesis and evaluation of N1-alkylindole-3-ylalkylammonium compounds as nicotinic acetylcholine receptor ligands. Bioorganic & Medicinal Chemistry. 2012-06, 20 (12): 3719–3727 [2021-07-22]. doi:10.1016/j.bmc.2012.04.050 （英语）.

[3] Christopher R. Jamison, Joseph J. Badillo, Jeffrey M. Lipshultz, Robert J. Comito, David W. C. MacMillan. Catalyst-controlled oligomerization for the collective synthesis of polypyrroloindoline natural products. Nature Chemistry. 2017-07-24, 9 (12): 1165–1169 [2021-07-22]. ISSN 1755-4330. doi:10.1038/nchem.2825.

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