CXCL9(英语:Chemokine (C-X-C motif) ligand 9)是一小分子的细胞因子属于CXC趋化因子家族,又被称作“干扰素伽玛诱导的单核细胞因子”(Monokine induced by gamma interferon, MIG)[1]。CXCL9是T细胞趋化因子[1]。干扰素伽玛诱导CXCL9的表达。人类的CXCL9与CXCL10,CXCL11的基因相邻聚集在第四染色体上[2]。CXCL9,CXCL10, CXCL11结合趋化因子受体CXCR3而起其细胞趋化作用[3][4]。
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参考文献
- ↑ 1.0 1.1 Liao F, Rabin RL, Yannelli JR, Koniaris LG, Vanguri P, Farber JM. Human Mig chemokine: biochemical and functional characterization. J Exp Med. 1995 Nov 1;182(5):1301-14.
- ↑ Lee HH, Farber JM. Localization of the gene for the human MIG cytokine on chromosome 4q21 adjacent to INP10 reveals a chemokine "mini-cluster". Cytogenet Cell Genet. 1996;74(4):255-8.
- ↑ Loetscher M, Gerber B, Loetscher P, Jones SA, Piali L, Clark-Lewis I, Baggiolini M, Moser B. Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med. 1996 Sep 1;184(3):963-9.
- ↑ Weng Y, Siciliano SJ, Waldburger KE, Sirotina-Meisher A, Staruch MJ, Daugherty BL, Gould SL, Springer MS, DeMartino JA. Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors. J Biol Chem. 1998 Jul 17;273(29):18288-91.