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本网站的医疗相关内容仅供参考，并不能视作专业意见。如需医疗服务或可靠意见，请咨询专业人士。| 抗磷脂综合征 | |
|---|---|
| 同义词 | Hughes syndrome[1] |
 | |
| Micrograph showing an advanced thrombotic microangiopathy, as may be seen in ALPA syndrome. Kidney biopsy. PAS stain. | |
| 分类和外部资源 | |
| 医学专科 | 风湿病学 |
| ICD-10 | D68.6 (ILDS D68.810) |
| ICD-9-CM | ICD9 289.81 |
| OMIM | 107320 |
| DiseasesDB | 775 |
| eMedicine | med/2923 |
| MeSH | D016736 |
抗磷脂综合征或抗磷脂抗体综合征（英语：antiphospholipid syndrome 或 英语：antiphospholipid antibody syndrome，缩写为APS或APLS）是由于人体免疫系统对细胞膜成分磷脂发生异常的自身免疫反应，产生抗体所引起的一组综合征。主要症状有动脉或者静脉血管栓塞、血小板减少以及与怀孕相关的胎死腹中、早产和自发性流产等，同时伴有抗心磷脂或者狼疮抗凝物实验持续阳性。
患者体内免疫功能失调会产生多种自身抗体。这些抗体引起血小板减少，同时破坏血管内皮细胞的完整性，导致血栓形成。怀孕妇女由于胎盘动静脉发生血栓，从而使得胎盘供血受阻，导致流产。
参考文献
- ↑ Hughes, Graham; Khamashta, Munther A. Hughes Syndrome: Highways and Byways. Springer Science & Business Media. ISBN 9781447151616 （英语）.
- Triona Holden. Positive Options for Antiphospholipid Syndrome (APS): Self-Help and Treatment. Hunter House (CA). 2003. ISBN 0-89793-409-1.
- Kay Thackray. Sticky Blood Explained. Braiswick. 2003. ISBN 1-898030-77-4. A personal account of dealing with the condition.
- Graham R V Hughes. Understanding Hughes Syndrome: Case Studies for Patients. Springer. 2009. ISBN 1-84800-375-7. 50 case studies to help you work out whether you have it.
- 原发性抗磷脂综合征诊疗指南
外部连接
- APS Foundation of America, Inc.
- Hughes Syndrome Foundation
- Hughes Syndrome: simple to treat but all too often ignored - Interview with Hughes; The Telegraph, 2 February 2009; Accessed 18 November 2016