2B类致癌物（英语：Group 2B carcinogens），为国际癌症研究机构（International Agency for Research on Cancer，IARC）对致癌物质的分类，此类物质（或其混合物）可能对人类致癌。其通常包括236类物质（如黄樟素、四氯化碳、电磁波、抗甲状腺药物丙硫氧嘧啶（propylthiouracil）、二异氰酸甲苯、抗艾滋病药物齐多夫定（zidovudine）、汽油引擎废气、干洗业等），对人类为有可能致癌物，对动物为很可能也是致癌物。[1]更多详细信息，可以搜寻国际癌症研究机构（IARC）专著。[2]
物质和物质组合
| 中文名称 | 学名 | CAS号 | 欧盟委员会编号 EINECS |
备考 |
|---|---|---|---|---|
| A-a-C (2-Amino-9H-pyrido[2,3-b]indole) | US Biological 化学试药类 | |||
| 乙醛 | Acetaldehyde | 0 | ||
| 乙酰胺 | Acetamide | 0 | ||
| Acétate de médroxyprogestérone | 0 | |||
| Acétate de méthylazoxyméthanol | 0 | |||
| 乙酸乙烯酯 | Acétate de vinyle | 0 | ||
| 咖啡酸 | Acide caféique | 0 | ||
| Acide chlorendique | 0 | |||
| Acide dichloroacétique | 0 | |||
| Acide nitrilotriacétique | 0 | |||
| Acrylate d'éthyle | 0 | |||
| 丙烯腈 | Acrylonitrile | 0 | ||
| 阿达帕林 | Adapalene | |||
| AF-2 | Furylfuramide 2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide |
硝基蚨喃类杀菌剂，结构类似对羟基苯甲酸酯 | ||
| 黄麹毒素 M1 | Aflatoxin，M1 | 2 | ||
| 对－氨基偶氮苯 | Aniline Yellow para-Aminoazobenzene |
0 | 苯胺黄 | |
| 邻－氨基偶氮甲苯 | ortho-Aminoazotoluene | 0 | 苏丹红IV代谢生成的物质 | |
| 2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole | 1 | |||
| 胺苯吖啶 | Amsacrine | 5 | 抗肿瘤药，别名安丫啶、安吖啶 | |
| 邻氨基苯甲醚 | ortho-Anisidine | 0 | ||
| 三氧化二锑 | Antimony trioxide | 1 | ||
| 异黄樟 | Aramite | 别名杀螨特；异黄樟；杀螨剂 | ||
| 金胺O | Auramine | 0 | 工业级（technical-grade） | |
| 重氮乙酰丝氨酸 | Azaserine | 0 | 别名氮丝氨酸；氮杂丝氨酸；重氮丝氨酸 - 用以抑制某些肿瘤生长的抗生素 | |
| 氮丙环 | Aziridine | 0 | ||
| Benz[j]aceanthrylene | （多环芳香烃，PAHs） | |||
| Benz(''a'')anthracene | 0 | （多环芳香烃，PAHs） | ||
| Benzo(b)fluoranthene | 0 | （多环芳香烃，PAHs） | ||
| Benzo(j)fluoranthene | 0 | （多环芳香烃，PAHs） | ||
| Benzo(k)fluoranthene | 0 | （多环芳香烃，PAHs） | ||
| Benzo(''c'')phenanthrene | 0 | （多环芳香烃，PAHs） | ||
| 苯并呋喃 | Benzofurane、Benzofuran | 0 | （多环芳香烃，PAHs） | |
| Benzyl violet 4B 酸性紫4B |
紫色1号，C39H40N3NaO6S2，3-[[Ethyl[4-[[4-(dimethyliminio)-2,5-cyclohexadiene-1-ylidene][4-[ethyl[3-(sodiooxysulfonyl)benzyl]amino]phenyl]methyl]phenyl]amino]methyl]benzenesulfonate | 1 | 主要用于羊毛、丝绸、锦纶的染色[3] | |
| 二溴新戊醇 2,2-双(溴甲基)-1,3-丙二醇 |
2,2-Bis(bromomethyl)propane-1,3-diol | 2 | 中间体或阻燃剂[4] | |
| 博来霉素 | Bleomycin | |||
| Bracken fern | 蕨类植物；[5][6][7] | |||
| 溴二氯甲烷 | Bromodichloromethane | 0 | ||
| 丁基羟基茴香醚 | Butylated hydroxyanisole | 4 | ||
| β-丁内酯 | b-Butyrolactone，别名4-甲基-β-丙酰内酯；B-丁内酯；Β-丁内酮，分子式为C4H6O2 | 2 | 酯类，可作单体[8] | |
| 碳烟 | Carbon black | |||
| 四氯化碳 | Carbon tetrachloride | |||
| 邻苯二酚 | Catechol | |||
| 氯丹 | Chlordane | |||
| 十氯酮 | （开蓬，杀虫﹑杀真菌药，原商标名） | |||
| 氯菌酸 | 六氯内-甲烯基-四氢苯二甲酸 | 毒性“气喘、肺水肿、过敏性皮肤炎、灼热疼痛感，视线模糊并流泪” | ||
| 4-氯苯胺 | para-Chloroaniline | 0 |
- 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone
- Chloroform
- 1-Chloro-2-methylpropene
- Chlorophenoxy herbicides
- 4-Chloro-ortho-phenylenediamine
- Chloroprene
- Chlorothalonil
- Chrysene
- CI Acid Red 114
- CI Basic Red 9
- CI Direct Blue 15
- Citrus Red No. 2
- Cobalt and cobalt compounds
- Cobalt sulfate and other soluble cobalt(II) salts
- Coconut oil diethanolamine condensate
- para-Cresidine
- Cycasin
- Dacarbazine
- Dantron (Chrysazin, 1,8-Dihydroxyanthraquinone)
- Daunomycin
- DDT (p,p'-DDT)
- N,N'-Diacetylbenzidine
- 2,4-Diaminoanisole
- 4,4'-Diaminodiphenyl ether
- 2,4-Diaminotoluene
- Dibenz[a,h]acridine
- Dibenz[a,j]acridine
- 7H-Dibenzo[c,g]carbazole
- Dibenzo[a,e]pyrene
- Dibenzo[a,h]pyrene
- Dibenzo[a,i]pyrene
- 1,2-Dibromo-3-chloropropane
- 2,3-Dibromopropan-1-ol
- Dichloroacetic acid
- para-Dichlorobenzene
- 3,3'-Dichlorobenzidine
- 3,3'-Dichloro-4,4'-diaminodiphenyl ether
- 1,2-Dichloroethane
- Dichloromethane (methylene chloride)
- 1,3-Dichloropropene (technical grade)
- Dichlorvos
- 1,2-Diethylhydrazine
- Diglycidyl resorcinol ether
- Dihydrosafrole
- Diisopropyl sulfate
- 3,3'-Dimethoxybenzidine (o-Dianisidine)
- para-Dimethylaminoazobenzene
- trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)-vinyl]-1,3,4-oxadiazole
- 2,6-Xylidine (2,6-Dimethylaniline)
- 3,3'-Dimethylbenzidine (o-Tolidine)
- 1,1-Dimethylhydrazine
- 3,7-Dinitrofluoranthene
- 3,9-Dinitrofluoranthene
- 1,6-Dinitropyrene
- 1,8-Dinitropyrene
- 2,4-Dinitrotoluene
- 2,6-Dinitrotoluene
- 1,4-Dioxane
- Disperse Blue 1
- 1,2-Epoxybutane
- Ethyl acrylate
- Ethylbenzene
- Ethylene dichloride
- Ethyl methanesulfonate
- Foreign bodies, implanted in tissues
- Polymeric, prepared as thin smooth films (with the exception of poly(glycolic acid))
- Metallic, prepared as thin smooth films
- Metallic cobalt, metallic nickel and an alloy powder containing 66-67% nickel, 13-16% chromium and 7% iron
- 2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole
- Fumonisin B1
- Furan
- Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole)
- Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)
- Glycidaldehyde
- Griseofulvin
- HC Blue No. 1
- Heptachlor
- Hexachlorobenzene
- Hexachloroethane
- Hexachlorocyclohexanes
- Hexamethylphosphoramide (HMPA)
- Human immunodeficiency virus type 2 (infection with)
- Human papillomaviruses: some types other than 16, 18, 31 and 33
- Hydrazine
- 1-Hydroxyanthraquinone
- Indeno[1,2,3-cd]pyrene
- Iron-dextran complex
- Isoprene
- Lasiocarpine
- Lead
- Magnetic fields (extremely low frequency)
- MeA-a-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole)
- Medroxyprogesterone acetate
- MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline)
- MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline)
- Merphalan
- 2-Methylaziridine (Propyleneimine)
- Methylazoxymethanol acetate
- 5-Methylchrysene
- 4,4'-Methylene bis(2-methylaniline)
- 4,4'-Methylenedianiline
- Methylmercury compounds
- 2-Methyl-1-nitroanthraquinone (uncertain purity)
- N-Methyl-N-nitrosourethane
- Methylthiouracil
- Metronidazole
- Michler's base (4,4'-methylene-bis(N,N-dimethyl)benzenamine)
- Michler's ketone (4,4'-bis(dimethylamino)benzophenone)
- Microcystin-LR
- Mirex
- Mitomycin C
- Mitoxantrone
- Monocrotaline
- 5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]-2-oxazolidinone
- Nafenopin
- Naphthalene
- Nickel, metallic and alloys
- Niridazole
- Nitrilotriacetic acid and its salts
- 5-Nitroacenaphthene
- 2-Nitroanisole
- Nitrobenzene
- 6-Nitrochrysene
- Nitrofen (technical-grade)
- 2-Nitrofluorene
- 1-[(5-Nitrofurfurylidene)amino]-2-imidazolidinone
- N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide
- Nitrogen mustard N-oxide
- Nitromethane
- 2-Nitropropane
- 1-Nitropyrene
- 4-Nitropyrene
- N-Nitrosodi-n-butylamine
- N-Nitrosodiethanolamine
- N-Nitrosodi-n-propylamine
- 3-(N-Nitrosomethylamino)propionitrile
- N-Nitrosomethylethylamine
- N-Nitrosomethylvinylamine
- N-Nitrosomorpholine
- N-Nitrosopiperidine
- N-Nitrosopyrrolidine
- N-Nitrososarcosine
- Ochratoxin A
- Oestrogen-progestogen therapy, postmenopausal
- Oil Orange SS
- Oxazepam
- Palygorskite (attapulgite) (long fibres, >5µm)
- Panfuran S (containing dihydroxymethylfuratrizine)
- Phenazopyridine hydrochloride
- Phenobarbital
- Phenolphthalein
- Phenoxybenzamine hydrochloride
- Phenyl glycidyl ether
- Phenytoin
- PhIP (2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine)
- Polychlorophenols and their sodium salts (mixed exposures)
- Ponceau MX
- Ponceau 3R
- Potassium bromate
- Progestins
- Progestogen-only contraceptives
- 1,3-Propane sultone
- β-Propiolactone
- Propylene oxide
- 丙硫氧嘧啶（Propylthiouracil、PTU），抗甲状腺药物
- Radiofrequency electromagnetic fields, such as, but not limited to, those associated with wireless phones [9]
- Refractory ceramic fibres
- Riddelliine
- 黄樟素Safrole
- Schistosoma japonicum (infection with)
- Sodium ortho-phenylphenate
- Special-purpose fibres such as E-glass and '475' glass fibres
- Sterigmatocystin
- Streptozotocin
- Styrene
- Sulfallate
- Tetrafluoroethylene
- Tetranitromethane
- Thioacetamide
- 4,4'-Thiodianiline
- Thiouracil
- Titanium dioxide
- 二异氰酸甲苯（2,4-Toluene diiso-cyanate, 2,4-TDI）[10]
- Trichlormethine (Trimustine hydrochloride)
- Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole)
- Trp-P-2 (3-Amino-1-methyl-5H-pyrido[4,3-b]indole)
- Trypan blue
- Uracil mustard
- Vanadium pentoxide
- Vinyl acetate
- 4-Vinylcyclohexene
- 4-Vinylcyclohexene diepoxide
- Zalcitabine
- 齐多夫定（Zidovudine，AZT）
混合物
接触场合
注释
- 脚注
- ^1 Evaluated as a group.
- ^2 There is limited evidence in humans that coffee drinking is carcinogenic in the urinary bladder.
- ^3 There is some evidence of an inverse relationship between coffee drinking and cancer of the large bowel.
引用
- ↑ 谈环境中的致癌物 - 台北荣民总医院 毒物科 杨振昌医师
- ↑ preamble to the IARC Monographs pdf
- ↑ 存档副本. [2014-11-24].
- ↑ [1][永久失效链接]
- ↑ Bracken Fern - Bracken Fern or Brake Fern (Pteridium aquilinum) - Plants toxic to animals - Veterinary Medicine library at U of Illinois
- ↑ 存档副本. [2014-11-24].
- ↑ 存档副本 (PDF). [2014-11-24].
- ↑ 存档副本. [2014-09-20].
- ↑ Press release No 208, 31 May 2011 , IARC classifies Radiofrequency Electromagnetic Fields as possibly carcinogenic to humans
- ↑ 2,4-二异氰酸甲苯健康危害 - 阳明大学环境卫生研究所